Preoperative gross classification of gastric adenocarcinoma: Comparison of double contrast-enhanced ultrasound and multi-detector row CT

Abstract

Objective To compare the accuracy of double contrast-enhanced ultrasound (DCEUS) and multi-detector row CT (MDCT) in determining the gross classification in patients with gastric carcinoma (GC) preoperatively. Methods 239 patients with GC proved by endoscopic biopsy were included. DCEUS (intravenous microbubbles combined with oral contrast-enhanced ultrasound) and MDCT were performed preoperatively. The diagnostic accuracy of DCEUS and MDCT in determining gross classification was calculated and compared. Results The overall accuracy of DCEUS in determining the gross appearance of GC was higher than that of MDCT (85% vs. 80%, P<0.05); there was no significant difference in accuracy between DCEUS and MDCT for BorrmannⅠ and Ⅳ classification of AGC (χ2=1.175, P=0.323 for type Ⅰ; χ2=2.171, P=0.141 for type Ⅳ); the accuracy of DCEUS for EGC, Borrmann Ⅱ and Ⅲ classification of GC was higher than that of MDCT (χ2=16.307, P=0.000 for EGC; χ2=39.950, P=0.000 for type Ⅱ; χ2=35.770, P=0.000 for type Ⅲ). Conclusion DCEUS is valuable in determining gross typing of gastric adenocarcinoma preoperatively. Key words: Stomach neoplasms; Ultrasonography; Tomography, spiral computed