Abstract
BackgroundThe staging of axillary lymph nodes is critical to the management and prognosis of breast cancer, the most frequent cancer in females. Neoadjuvant therapy and lymph node dissection are recommended when malignant cells invade the lymph nodes. Therefore the pre-operative examination of these lymph nodes is crucial to treatment.MethodsIn this study, we examined the effectiveness of cytology through ultrasound-guided fine needle aspiration (USG-FNA) and ultrasound (US) imaging using an established classification system in correctly identifying lymph node status compared to the final histological results after surgery.ResultsCytology by USG-FNA and US classification were found to be promising methods of axillary lymph node staging.ConclusionsUS and CB offer minimally invasive techniques to pre-operatively examine these lymph nodes in patients with primary breast cancer.
Highlights
The staging of axillary lymph nodes is critical to the management and prognosis of breast cancer, the most frequent cancer in females
The goal of this study was to compare the results of axillary lymph node status by cell-block obtained through fine-needle aspiration [7] and by axillary ultrasound, according to a classification system derived from Stavros [8]
Axillary lymph node status is an important component of staging and treatment planning in breast cancer
Summary
The staging of axillary lymph nodes is critical to the management and prognosis of breast cancer, the most frequent cancer in females. Methods: In this study, we examined the effectiveness of cytology through ultrasound-guided fine needle aspiration (USG-FNA) and ultrasound (US) imaging using an established classification system in correctly identifying lymph node status compared to the final histological results after surgery. Conclusions: US and CB offer minimally invasive techniques to pre-operatively examine these lymph nodes in patients with primary breast cancer. Axillary lymph node status is an important factor in the prognosis and management of breast cancer. Several methods to detect positive axillary lymph nodes during the pre-operative diagnosis have been evaluated, including ultrasound-guided fine needle aspiration (USG-FNA) cytology, ultrasoundguided biopsy and, as an imaging method, axillary ultrasound [5]. If a positive lymph node is not found during the pre-operative evaluation, a less invasive sentinel node biopsy will be utilized instead of axillary lymph
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