Abstract
RESULTS: The SFRP2 contrast agent detected tumor vasculature with greater signal intensity (SI) using 5e7 vs 5e6 microbubbles (21.2 vs 2.4 SI, p<0.001) and contrast with 3-fold greater antibody conjugation (27.6 vs 14.8 SI, p<0.001). Using these optimizations, SFRP2 contrast agent detected a 2.8-fold greater tumor vasculature SI compared with control (22.1 vs 7.92 SI, p<0.001). Peritumoral vasculature showed minimal SI for both the SFRP2 and control contrast agents, (3.2 vs 1.6, p1⁄40.16), confirming specificity of the SFRP2 contrast for tumor vasculature.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
