Prenatal growth of live weight and coat color of the mini pigs of ICG SB RAS

Abstract

The article considers the possibility of connection of KIT and MC1R loci with prenatal growth of mini pigs of the breeding group of Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences (ICG SB RAS). It is assumed that this relationship may be the result of increased variability of the sign – the mass of the newborn pig in heterozygous according to the loci of individuals. Since prenatal growth is affected by a number of factors that affect the weight of the newborn pig, instead of the absolute value of the sign – the mass of the individual in kilograms, a relative one was used, which is the ratio of the mass of a particular individual to the average mass of the individual in the nest in which it was born. The study showed that mini-pigs of ICG SB RAS have a relationship between heterozygosity at MC1R and KIT loci and increased concentration of individuals in the modal class of relative weight distribution at birth. The discovered relationship is the result of the interaction of increased variability of mass at birth in individuals’ heterozygous loci, controlling intracellular metabolism, with the vector of phenotypic realization of the genetic potential of growth of individuals in the prenatal period. The decomposition of the specified vector into components showed that optimizes forming the kurtosis variation of the number of components dominate in individuals with domestication coat color, while in individuals with pseudoagouti coat color – biasing, forming the asymmetry of the distribution. The results of the study also showed that the genotypes at the loci MC1R and KIT do not affect the competitive relationship between the fetuses during the prenatal period . In addition, the analysis of the consistency of the estimates of individual classes of variational series of individuals of different races to a normal distribution showed that the mini pigs of ICG SB RAS alleles present low weight at birth, inherited from the Vietnamese breeds , and alleles of the high mass at birth, inherited from the Large White and/or Danish Landrace breed.