Abstract
Prenatal alcohol exposure alters the liver and induces pathological changes the morphology and function of the Golgi apparatus (GA), including an accumulation or reduced transport of newly synthesized glycoconjugates which suggests that ethanol could affect the cytoskeleton (CSK) hepatocytes. To test this possibility we have analysed, using various techniques, the effect of ethanol in utero on several CSK proteins including actin, alpha- tubulin, cytokeratin, vimentin and the motor associated proteins dynein and kinesin. Our results show that this treatment increases the amount of both alpha -tubulin and cytokeratin and alters its distribution.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: The International Journal of Developmental Biology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.