Prenatal diagnosis of the pronounced form of amniotic band sequence in the I trimester of gestation

Abstract

The case of early prenatal diagnosis of multiple congenital malformations of the fetus caused by amniotic bands is presented. Ultrasound examination at 13 weeks of gestation revealed exencephaly, ectopia of the heart, fixed position of the fetus, short umbilical cord, generalized soft tissue edema, amniotic bands. A pathological examination based on the detected amniotic fibrous bands covering the head, trunk and umbilical cord of the fetus confirmed the diagnosis. It was identified that the fetus additionally had: anophthalmia, dysplasia of the auricles, atresia of the auditory canals, dysplasia of the upper and lower jaws, cleft lip, agenesis of the sternum, gastroschisis, contracture of the right elbow joint.