Prenatal diagnosis of isolate fetal cleft palate by two-dimensional ultrasonography

Abstract

Objective To discussion the value of palate standard section in prenatal ultrasound diagnosis of isolate cleft palate, and summarize the two-dimensional ultrasound characteristics of isolate cleft palate. Methods Two-dimensional ultrasound was performed in 18 073 fetuses during 18 to 40 gestational weeks of pregnancy. Fetal palate structure were scanned through the oral cleft, the cheek, the neck part, and the standard sagittal section, transverse section and coronal section were obtained to diagnosis cleft palate. The results were compared with labour or postpartum findings. Results In 18 073 cases, 20 cases of isolate cleft palate, 19 cases were diagnosed as fetal isolate cleft palate by prenatal ultrasonography, of which 18 cases were correctly diagnosed, 1 case was misdiagnosed, 1 case was missed diagnosed. The sensitivity, specificity, accuracy of prenatal ultrasound detection were 95%, 100%, 95%, respectively. The ultrasonic characteristics of isolate cleft palate: lack of crack were located in the midline, soft cleft palate was shown as the midline of soft palate interrupted, short of crack was >< , ‖ , / [HT5 ] shape, hard cleft palate was shown as the midline of hard palate interrupted, short of crack was open back V or U shape. Conclusions The palate standard section has high value in prenatal ultrasound diagnosis of cleft palate, which can assess fracture morphology, length, width, direction and involving range. Key words: Ultrasonography, prenatal; Cleft palate