Abstract
The possibility of performing an early noninvasive prenatal diagnosis on fetal cells isolated from maternal peripheral blood is an important goal for modern obstetric care. A recent retrospective Italian study was carried out by accessing the results of cytogenetic analysis of amniotic fluid in women with less than and greater than 35 years and performed during years 1995 to 1996. The entity of the trafficking of the fetal cells depends by many factors such as complicated pregnancies and by the modes of releasing them in maternal circulation. The major limitation that continues to overwhelm the clinical use of fetal cells is their extremely low number into maternal circulation, considered not yet sufficient to perform an accurate genetic analysis. An elevated number of fetal cells in maternal blood have been observed in some pregnancy-related disorders and as pregnancies affected by fetal trisomies, pre-eclampsia, eclampsia, intrauterine growth restriction, or polyhydramnios with respect to normal pregnancies.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
