Prenatal AD.VEGF gene therapy increases fetal growth velocity and alters uterine artery vascular reactivity in the absence of a measurable effect on uterine blood flow in a sheep model of fetal growth restriction

Abstract

IntroductionAdenovirus (Ad) mediated over-expression of vascular endothelial growth factor (VEGF) in the uterine artery (UtA) enhances pre- and postnatal growth in growth-restricted sheep fetuses (Carr 2011a/2011b). Herein effects on uterine...