Premature ejaculation: is there an efficient therapy?

Fábio Barros De Francischi,Ricardo Eidi Itao,Jose Germano Ferraz Del Arruda,Daniel Cernach Ayres,Luis Cesar Fava Spessoto,Fernando Nestor Facio Junior

doi:10.1590/s1679-45082011rb1929

Fábio Barros De Francischi, Ricardo Eidi Itao + Show 4 more

Open Access

https://doi.org/10.1590/s1679-45082011rb1929

Copy DOI

Abstract

Premature ejaculation is the most frequent male sexual dysfunction, estimated to affect 20 to 30% of men at some time in their life. A Pubmed search from the year 2000 to the present was performed to retrieve publications related to management or treatment of premature ejaculation. Behavioral techniques have been the mainstay of premature ejaculation management for many years, although evidence of their short-term efficacy is limited. Topical therapies for premature ejaculation act by desensitizing the penis and do not alter the sensation of ejaculation. Selective serotonin reuptake inhibitors (SSRIs), commonly used in the treatment of depression, are often used to treat premature ejaculation, based on the observation that delayed ejaculation is a frequent side effect of this drug class. Dapoxetine is a short-acting SSRI formulated to treat premature ejaculation, and results seem very promising.

Highlights

Premature ejaculation (PE) is the most frequent male sexual dysfunction with an estimated 20 to 30% of men at some time in their life(1)
A Pubmed search from the year 2000 to the present was performed to retrieve publications related to management or treatment of PE, or male sexual dysfunction
Waldinger et al(4) advocated the use of activityspecific terms for ejaculation latency time (ELT) rather than a more global term such as “penetration ejaculation latency time”, which would include any sexual activity except masturbation and manual stimulation by partner

Summary

INTRODUCTION

Premature ejaculation (PE) is the most frequent male sexual dysfunction with an estimated 20 to 30% of men at some time in their life(1). Attempts to explain the etiology of PE included a diverse range of biological and psychological theories. Most of these proposed etiologies are not based on evidence and are speculative at best. A ejaculação precoce é a disfunção sexual masculina mais frequente, com uma estimativa de acometimento de 20 a 30% dos homens em algum momento da vida. Os inibidores seletivos da recaptação da serotonina são utilizados para depressão e, em geral, também para tratar ejaculação precoce, com base na observação de que o retardo na ejaculação é um efeito colateral frequente dessa classe de drogas. A dapoxetina é um inibidor seletivo da recaptação da serotonina de curta ação, que foi formulado para tratar a ejaculação precoce, e seus resultados parecem muito promissores. Descritores: Ejaculação; Coito; Disfunção erétil; Comportamento sexual; Educação sexual; Inibidores de captação de serotonina

METHODS

DISCUSSION

Findings

CONCLUSION