PREMATURE AND FAVORABLE VASCULAR AGING IN YOUNG PEOPLE TAKING INTO ACCOUNT BLOOD PRESSURE

Abstract

Abstract Objective: Features of vascular aging in young people have been studied very poorly to date. Meanwhile, increased vascular stiffness is regarded by experts as a realized risk factor. Purpose was to assess the representation of different variants of elastic vascular potential in young people depending on the level of blood pressure and taking into account sex. Design and method: 243 freshmen students including 81 boys and 162 girls were examined on the basis of the Health Center of StSMU within the framework of the National Preventive Project University is Territory of Health. All the examined patients were divided into quartile groups according to such an indicator of vascular stiffness as cardiovascular vascular index or CAVI, which was determined using the diagnostic complex VaSera-1500, Fucuda Denshia, Japan. According to some experts, the fourth quartile of this distribution corresponds to early vascular aging or EVA syndrome. The first quartile corresponds to favorable vascular aging. Then the representation of carriers of prehypertension (PH) and arterial hypertension (AH) in each of the four quartile groups was analyzed. The same analysis was carried out among carriers of normotension and hypotension. Data processing was carried out using the software package Statistica 10.0, StatSoft Inc, USA. Results: The representation of both boys and girls with normal and reduced blood pressure is slightly higher in the first quartile CAVI-group. The representation of young men with increased blood pressure is also somewhat greater in the first quartile CAVI-group. The bulk of girls with high blood pressure is represented in the first and second quartile CAVI-groups. Conclusions: Among freshmen with different levels of blood pressure there are carriers of different variants of elastic vascular potential. At the same time, regardless of the BP level, carriers of favorable vascular aging dominate among young people. Cases of premature vascular aging also occur among individuals with any level of blood pressure. This suggests the need for an optimized approach to the formation of youth groups of cardiovascular risk, taking into account not only traditional risk factors such as hypertension, but also the characteristics of vascular elastic status.