Abstract
This paper describes two methods to aid interpretation and quantification of SPECT or PET images. In the first method 3D SPECT or PET data sets are aligned and scaled to a 3D MRI data set of the same patient using 4 skin markers visible on each modality. Three display schemes have been implemented for viewing the aligned slices. Examples of these displays are provided. The second method uses a labelled 3D MRI reference data set from a volunteer to identify major anatomical structures. The MR reference data set is aligned with the isotope image using the same 4 markers plus a marker on the vertex of the skull. The reference data set is segmented approximately into the major tissue types - cerebrospinal fluid (CSF) and grey and white matter. Major structures are identified via labels in the 3D data set. A linked cursor aids delineation of anatomical regions on the isotope image using the outline of structures on the reference data set as a template. Directions for future research in the generation of complete digital anatomical atlases, which include inter-individual variations, are outlined.
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