Preliminary study on non-contrast-enhanced whole-heart coronary magnetic resonance angiography at 3.0 T to evaluate the coronary stenosis

Abstract

Objective To evaluate the clinical value of non-contrast-enhanced whole-heart coronary magnetic resonance angiography (CMRA) at 3.0 T to diagnose coronary artery stenosis. Methods Thirty-three consecutive patients with significant coronary artery stenosis (>50%) on coronary computed tomographic angiography (CCTA) and who were scheduled for coronary angiography (CAG) were recruited for CMRA.CMRA was performed on a 3.0 T scanner with 32-element matrix coil.A non-contrast-enhanced,ECG-triggered,navigator-gated,T2prepared and fatsaturated 3-dimensional GRE sequence was employed.Using beta blockade to reduce the heart rate to less than 80 bpm.The quality at proximal-middle and distal segments of coronary artery between CMRA and CCTA was compared with Wilcoxon rank test.Using CAG as gold standard to evaluate the accuracy of CMRA to detect proximal-middle segments of coronary artery stenosis>50% diagnosed and the agreement between CMRA and CCTA were calculated. Results Among the 33 patients,30 patients successfully finished CMRA.The score at proximal-middle segments of coronary artery evaluated by CMRA and CCTA was similar (CMRA:3.49±0.61,CCTA:3.56±0.55,Z=- Key words: Coronary artery stenosis; Magnetic resonance angiography; Tomography,spiral computed; Coronary angiography