Abstract
MAGAT gel dosimeter with boron is irradiated in Heavy Water Neutron Irradiation Facility (HWNIF) of Kyoto University Research Reactor (KUR). The cylindrical gel phantoms are exposed to neutron beams of three different energy spectra (thermal neutron rich, epithermal and fast neutron rich and the mixed modes) in air. Preliminary results corresponding to depth-dose responses are obtained as the transverse relaxation rate (R2=1/T2) from magnetic resonance imaging data. As the results MAGAT gel dosimeter has the higher sensitivity on thermal neutron than on epi-thermal and fast neutron, and the gel with boron showed an enhancement and a change in the depth-R2 response explicitly. From these results, it is suggested that MAGAT gel dosimeter can be an effective tool in BNCT dosimetry.
Highlights
Boron-neutron capture therapy (BNCT) is a promising cancer therapy using the nuclear reaction of 10B with thermal neutron (< 0.5 eV) [1, 2]. 10B is delivered selectively to tumor-cells by boron carriers such as BPA (p-boronophenylalanin) and BSH
In the thermal neutron mode (Mode-1), both profiles of the gels with and without boron show monotonically decreasing with depth after the peak near the surface
It seems that the decrease for the gels with boron corresponds to decreasing of thermal neutron in tissue and the peak shifts to near the surface significantly due to the reaction with boron
Summary
Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8530, Japan
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