Abstract

Abstract D3Cr muscle mass, grip strength, leg extension 1-rm max (Keiser), and walking speed (400m usual walk) were collected with standardized protocols. We calculated sex-stratified unadjusted Pearson correlation coefficients, and partial Pearson correlation coefficient adjusted for body size (height, weight). D3Cr muscle mass was positively correlated with grip strength (men: unadjusted r=0.28, p<.001; women: unadjusted r=0.16, p=0.02) and leg extension strength (men: unadjusted r=0.44, p<.001; women: unadjusted r=0.31, p<.001). D3Cr muscle mass was correlated with 400-m walk speed only after adjustment for body size among both men (partial r=0.29, p<.001) and women (partial r=0.16, p=0.02). Associations of total thigh muscle volume by MRI with strength and walking speed were of similar magnitude to the association between D3Cr muscle mass with strength and walking speed.

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