Abstract
Background: The surgical management of breast cancer patients with infiltrated axillary lymph nodes (ALNs) at diagnosis is controversial, as some centres perform upfront axillary dissection (AD) while other centres perform the sentinel node (SN) mapping, so that some patients may benefit from the ACOSOG Z0011 trial criteria to skip further surgery. The primary aim of the MUTAS trial is to establish if performing the SN in breast cancer patients with confirmed infiltrated ALNs could be useful to tailor axillary surgery.
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