Abstract

在各种治疗肝纤维化的方法中,以肝星状细胞(HSC)为靶点成为目前的研究热点 [1-2].国艳等 [3]研究发现,莪术油注射液对体外培养的HSC有明显促凋亡作用,但其凋亡机制尚不清楚.我们进一步检测和证实了莪术油注射液对HSC的促凋亡作用;并同时检测促凋亡基因Fas、抑凋亡基因bcl-2与凋亡蛋白酶caspase-3,试图揭示莪术油注射液促进HSC凋亡作用的可能机制。

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