Preliminary phytochemical and analgesic activity extract of Kigelia pinnata leaf

Abstract

Kigelia pinnata Linn. (Balam Kheera) belongs to the family of Bignoniaceae and is commonly called the "sausage" tree because of its hugs fruits. The present research was conducted to investigate the analgesic activity of different extracts of leaves of Kigelia pinnata. Preliminary phytochemical investigations were performed by chemical tests. In the preliminary phytochemical test, the leaves extract showed the presence of phytosterols, alkaloids, glycosides, flavonoids, saponins, tannins, and phenolic compounds. An acute toxicity study was performed according to OECD guidelines. The analgesic activity was conducted by Hot Plate Method and Tail Immersion Test on adult Swiss albino mice. In Acute Toxicity Study, oral administration of extract was found safe at a dose of 2,000 mg/kg, p.o. and produced no signs of toxicity. The methanolic extract was found to be significant in Analgesic activity.