Abstract
Objective: To evaluate the preliminary phytochemical analysis and in vitro- Antihelmenthic activity of leaf extract of Achyranthes aspera. Background: Achyranthes aspera is an annual, stiff-erect herb found commonly as a weed throughout India. The leaf ethyl acetate extract showed high larvicidal activity on the tick larvae of Rhipicephalus. It strengthen the liver and kidneys, strengthening muscles, tendons and bones, anti-inflammatory, anti-toxin, urine laxative, normalize menstruation, hemostatic, ease childbirth. Chemical Ingredients includes Akirantin, glokosa, galactose, reilosa, ramnosa, and alkaloids. Hentriakontan, sapogenin, Betaine, ecdysterone, triterpenoid saponins. Methods: Preliminary phytochemical analysis was done by adopting the method of Evans. Antihelmenthic assay is performed by standard protocol. Result: The present study reveals the presence of few secondary metabolites and the extract exhibitspotent Antihelmenthic activity. Conclusion: From the present study it can be concluded that Achyranthes aspera leaf extract possessed marked in vitro Anti helminthic effect.
Highlights
Achyranthes aspera L. (Amaranthaceae) is distributed as weed throughout India, tropical Asia and other parts of the world.[1,2,3] The plant is a popular folk remedy in traditional system of medicine throughout the tropical Asian and African countries
The ethanolic extract so obtained from the dried leaf powder of A. aspera, were tested for the presence and absence of the phytochemicals
Achyranthes aspera stem extract has been proved to possess the anti helmenthic activity, A.aspera leaf extract were tested at various concentation against adult earthworm
Summary
• Achyranthes aspera leaf showed prominent anti-helmenthic activity. • Achyranthes aspera leaf showed presence of phytochemical constituents. • Achyranthes aspera is used in management of inflammatory disorders, cough, bronchial asthma. • Achyranthes aspera leaf extract were reported to posses thyroid stimulating and antiperoxidative properties. • Achyranthes aspera strengthen the liver and kidneys, strengthening muscles, Abbreviations used: A. aspera: Achyranthes aspera, DMSO: Dimethyl sulfoxide. Correspondence: Ms Thangavelu Lakshmi, Assistant professor, Department of Pharmacology, Saveetha Dental College and Hospitals, Chennai, T.N, India. Phone no: 09884708887
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