Abstract
Introduction: Lepa is a bahirparimarjana chikitsa that helps in bringing samyata in sthanika dosha and dhatu. Many lepa are mentioned in Ayurveda pharmaceutics for the treatment of mukhadooshika. Among it, one is a combination of Lodhra, Kustumburu, Vacha, Vatapallava, and Narikelashuktya. Mukhadooshika is a type of kshudraroga, featuring the formation of pidaka on face. The symptoms of mukhadooshika resembles with acne vulgaris. Aim: An attempt is made to analyze the physico-chemical parameters of the mukhadooshikahara lepa churna. Materials and methods: The pharmaceutical preparation is easy and simple with easily available ingredients. The organoleptic characters like appearance, odour, taste and physico-chemical parameters like pH, total ash. Water Soluble ash, Alcohol soluble extractives, Water soluble extractives, loss on drying and HPTLC were carried out. Observations and results: The obtained results were discussed in the present paper. Discussion and conclusion: Mukhadooshikahara lepa churna is a simple preparation and can be prepared by easily available drugs. HPTLC fingerprinting at different wavelengths was carried out. At 254 nm, 366nm and 620nm 11, 8 and 10 peaks were found with different retention factor starting from 0.02 to 0.80, 0.03 to 0.096 and 0.07 to 0.80respectively. The analytical study findings can be taken as a preliminary standard for mukhadooshikahara lepa churna.
Highlights
Lepa is a bahirparimarjana chikitsa that helps in bringing samyata in sthanika dosha and dhatu (1)
Many lepa are mentioned in Ayurveda pharmaceutics for the treatment of mukhadooshika
Analytical studies and HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY (HPTLC) conducted on the study drug have helped to develop preliminary standards for Mukhadooshikahara Lepa churna
Summary
Lepa is a bahirparimarjana chikitsa that helps in bringing samyata in sthanika dosha and dhatu. One is a combination of Lodhra, Kustumburu, Vacha, Vatapallava, and Narikelashuktya. Aim: An attempt is made to analyze the physico-chemical parameters of the mukhadooshikahara lepa churna. Discussion and conclusion: Mukhadooshikahara lepa churna is a simple preparation and can be prepared by available drugs. HPTLC fingerprinting at different wavelengths was carried out. The analytical study findings can be taken as a preliminary standard for mukhadooshikahara lepa churna. Many lepa are mentioned in Ayurveda pharmaceutics for the treatment of mukhadooshika. One is a combination of Lodhra, Kustumburu, Vacha, Vatapallava, and Narikelashuktya (2) (Table 1). The symptoms of mukhadooshika resembles with acne vulgaris. Wide range of treatment exists for Acne vulgaris which include both topical application and oral medicine.
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