Abstract
ABSTRACT Prolactin activity of human whole blood was concentrated by means of acid acetone extracts, using the Sulman method for the extraction of chromatophorotropic activity. These extracts were assayed by a single-injection local pigeon crop-weight technique. No prolactin activity was found in extracts obtained from the blood of children, of normal young men, and of normal young women in the first half of the menstrual cycle. On the other hand, extracts obtained from the blood (equivalent to 2.5 ml. whole blood) of young women in the second half of the menstrual cycle induced crop-weight responses of the same order of magnitude as induced by 0.05 I.U. of authentic prolactin, and activity greater than this was found in extracts obtained from the blood of lactating postpartum women. These observations constitute physiologic evidence that prolactin activity was measured, since prolactin activity was found only in those circumstances that would be expected on the basis of the known physiologic activity of ...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: The Journal of clinical endocrinology and metabolism
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
