Abstract
Changes in blood, hepatopancreas and kidney urea concentrations in O. verruculatum have been assessed in response to endocrinological provocations. Two hr after pleurovisceral (PV) ganglion removal blood and nephridial urea levels were found to be significantly lowered and elevated respectively, whereas the hepatopancreas urea value remained unaltered, over the sham control. Unboiled and boiled macerates of PV (2 gn/animal) ganglion were effective in significantly inhibiting urea levels in blood and kidney of normal intact individuals. The possibility of a neurohormone from the PV, influencing tissue urea levels is discussed.
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