Abstract
Background: Keratoconus (KC) is a visually debilitating disease if left undiagnosed and untreated. Early intervention is necessary to ensure a good quality of life for those afflicted by the disease. Although much research has been done in other parts of the world, there is a paucity in the literature that describes the disease from a South African perspective.Aim: The aim of this study was to provide the demographics of KC patients attending a university-based contact lens clinic between January 2007 and December 2017.Setting: Patients diagnosed with KC (N = 206) at a university-based contact lens clinic in Johannesburg, South Africa, were included in this analysis.Methods: A retrospective analysis of clinical records of 206 KC patients was conducted. Demographic data on race, gender, age and severity of disease were analysed and presented.Results: The majority of patients with KC that attended the clinic were female (53%), of mainly African (74%) descent and in their second decade of life. The average age at first visit was 24.0 ± 8.53 and 22.9 ± 7.46 years for males and females, respectively. There was no significant difference in average age between male and female patients (p 0.05). Patients in the first and second decade of life presented at first visit with a greater severity of disease when compared with those in the third decade or older.Conclusion: There is a dire need for larger epidemiological studies to be conducted on South African patients with KC so that early intervention becomes possible. This would greatly influence the quality of life for these patients and positively impact the socio-economic status of the country.
Highlights
IntroductionKerato (cornea) and Konos (cone) are Greek words from which the term keratoconus (KC) is derived
Kerato and Konos are Greek words from which the term keratoconus (KC) is derived
Every patient that attended the contact lens clinic underwent a thorough eye examination, which included a tomography evaluation with the Pentacam 70700 (Oculus, Wetzlar, Germany). Those patients who were diagnosed as having KC and had at least one good quality Pentacam scan were included in the analysis
Summary
Kerato (cornea) and Konos (cone) are Greek words from which the term keratoconus (KC) is derived. The literal translation, that is, cone-shaped cornea, is the fundamental characteristic that defines the disease. It is well established that KC is a bilateral, asymmetrical, non-inflammatory thinning of the cornea, which leads to high amounts of irregular corneal astigmatism, corneal bulging and sometimes distortion or scarring in various parts of the cornea.[1]. Keratoconus remains poorly defined in several aspects. As presented in many reviews of KC,[1,2,3] gender predominance remains uncertain. Keratoconus (KC) is a visually debilitating disease if left undiagnosed and untreated. Much research has been done in other parts of the world, there is a paucity in the literature that describes the disease from a South African perspective
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