Preliminary clinical application of magnetic resonance perfusion imaging of avasaular necrosis of femoral head

Abstract

Objective To evaluate the features and value of magnetic resonance (MR) perfusion imaging (PI) of avascular necrosis of the femoral head (ANFH). Methods MR, gadolinium (Gd)enhanced MR and MRPI were performed in 21 patients with a probable diagnosis of ANFH. Results MRI showed that 10 of the 21 patients were with ANFH,5 in bilateral femoral heads, and 5 in unilateral femoral head, totally in 15 femoral head, 2 at the Froberg stage Ⅰ , 4 at the stage Ⅱ, 2 at the stage Ⅲs, and 7 at the stage Ⅳ. Gd-enhanced MR showed that 2 femoral heads were not enhanced, 10 were slightly enhanced,reduction) was decreased with or without prolonged TrP(time to peak), the MTT (mean transit time) was declined, and then slowly increased (n=2). Conclusion MRPI reflects the blood perfusion of the femoral head. The type of the MRPI cure reflects the pathological progression of ANFH, evaluates the activity of the femoral head, and is useful to the clinical physicians to estimate the stage of ANFH and choose treatment for the patients. MRPI is a method in diagnose ANFH at the initial microcirculatory injury stage. Key words: Femur head necrosis; Magnetic resonance imaging; Hormones