Abstract
Objective To evaluate the value of endorectal ultrasound(ERUS)combined with real-time elastography in the staging of advanced rectal cancer in elderly patients. Methods A total of 50 patients with advanced rectal cancer underwent endorectal ultrasound and real-time tissue elastography imaging at our hospital from Jun. 2014 to Oct. 2015. Their staging results were compared with postoperative pathology. Results The accuracy, sensitivity and specificity of ERUS in the staging of advanced rectal cancer(T3)were 90%(45/50), 93.5%(43/46)and 50%(2/4), respectively. The accuracy, sensitivity and specificity of real-time elastography in the staging of advanced rectal cancer(T3)were 84%(42/50), 89.1%(41/46)and 25%(1/4), respectively. With the combination of the two techniques, the accuracy, sensitivity and specificity in the staging of advanced rectal cancer(T3)were 96%(48/50), 97.8%(45/46)and 75%(3/4), respectively. There was no significant difference in accuracy and sensitivity(χ2=4.000 and 3.100, P=0.373 and 0.542)between the three approaches. Kappa values between each of the three approaches and surgical pathology were 0.531, 0.252 and 0.728, respectively. Conclusions Real-time tissue elastography in the diagnosis and staging of advanced rectal cancer can be enhanced when used in combination with endorectal ultrasound. Key words: Rectal neoplasms; Elasticity imaging techniques
Published Version
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