Abstract
Objective To explore the imaging features of papillary thyroid microcarcinoma(PTMC) with real-time contrast-enhanced ultrasound. Methods One hundredand forty-three cases with 149 thyroid nodules(no diffuse lession) were divided into two groups according to the diameter size(group 1, <0.5 cm; group 2, 0.5-1.0 cm) and examined by contrast-enhanced ultrasound during preoperation. Pathology was followed up as golden diagnosis criteria. Results Seventy-five benign tumors and 74 PTMC were confirmed by pathology. There were significant differences in echoes homogeneity between benign and malignant tumors in group 2(W=1 029.5, Z=-5.524, P=0.000) but no in group 1(W=933.0, Z=-1.738, P=0.082). And nonhomogeneous enhancement were showed in most PTMC in group 2. But most PTMC showed homogeneous enhancement in group 1. Conclusions Contrast-enhanced ultrasound is valuable in diagnosis of PTMC with the diameter size of 0.5-1.0 cm. Key words: Ultrasonography; Microbubbles; Thyroid neoplasms
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