Abstract

The application of genetic technologies to the field of reproductive medicine has ushered in a new era of medicine that is likely to greatly expand in the coming years. Concurrent with an in vitro fertilization (IVF) cycle, it is now possible to obtain a cellular biopsy from a developing embryo and genetically evaluate this sample with increasing sophistication and detail. Information obtained from this analyzed sample may then guide which embryos are selected for uterine transfer. Applications for this technology are currently being employed to avoid the propagation of certain genetically based diseases and to increase the efficiency of assisted reproductive technologies in general. The way such technologies are implemented, however, has caused a continuous and ever evolving debate among reproductive medicine physicians and geneticists. This article will define the current uses of preimplantation genetic testing and discuss the benefits and limitations of this technology.

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