Abstract

Prehospital Plasma Resuscitation in Patients With Traumatic Brain Injury

Highlights

  • In this issue of JAMA Network Open, Gruen and colleagues[1] report on the association between prehospital resuscitation with plasma and survival in patients with traumatic brain injury (TBI)

  • Does plasma resuscitation reduce deaths attributed to hemorrhage in patients with multiple trauma and TBI? And do patients without TBI truly derive no benefit?

  • Hypoperfusion, shock, and brain injury can all compromise the endothelium, leading to derangements in hemostasis that may be profound when severe TBI occurs with concomitant extracranial injuries.[5]

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Summary

Introduction

In this issue of JAMA Network Open, Gruen and colleagues[1] report on the association between prehospital resuscitation with plasma and survival in patients with traumatic brain injury (TBI). The study by Gruen and colleagues[1] is important because it shows that a routinely available intervention may be associated with substantial improvement in TBI survival.

Results
Conclusion
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