Pregnancy Through Assisted Conception After Radical Trachelectomy: A Case Report

Abstract

Introduction: Trachelectomy, a conservative surgery in the early stages of cervical cancer, allows young women to keep their fertility. Infertility after such a surgery is frequent, and many couples should opt for assisted reproduction. Objectives: This case report aims to present a successful pregnancy in a woman with a history of cervical cancer and complete removal of the uterine cervix through trachelectomy. Case Presentation: A successful pregnancy is described after two failed attempts of embryo transfer (ET) in a 32-year-old woman with a history of trachelectomy due to stage IA invasive squamous cell carcinoma of the cervix. Before and after radical trachelectomy, she received adjuvant chemotherapy. In her second course of in-vitro fertilization, after a mock transfer at the time of ovum pickup with 11 oocytes and 7-day 3 embryos, her third ET cycle under ultrasound guide was successful. During pregnancy, in the first-trimester screening, nuchal translucency was reported to be 4.5 mm. Therefore, chorionic villous sampling and comparative genomic hybridization CGH-Array were performed before preparing for abdominal cerclage at 14 weeks. Further screening tests were normal. Finally, she delivered a 2430 g healthy baby girl through cesarean section at 37 weeks. Conclusions: The mock transfer and ultrasound-guided ET are suggested for women with a history of trachelectomy.