Abstract

In the current article, 3 cases of aortic aneurysm and dissection in pregnant patients with Marfan's syndrome are reported. It is well known that pregnancy is a risk factor for the development of aortic aneurysm and dissection in women with Marfan's syndrome since it is shown that dissection can develop both before and after labor. Marfan patients with an aortic root diameter greater than 4 cm should undergo preconceptual counseling for surgical aortic repair before pregnancy. Pregnant Marfan patients with an aortic aneurysm should be closely and continuously evaluated by multidisciplinary specialists in order to prevent possible aortic dissection that could be fatal for both the mother and the fetus.

Highlights

  • Aortic dissection (AD) is a serious condition with possible lethal outcome (1)

  • Concerning the facts mentioned above, the current study demonstrates our experience in diagnosing and treating an aortic aneurysm and dissection in pregnant patients with Marfan’s syndrome

  • Case Report 1 A 30-year-old patient with Marfan’s syndrome showing prepregnancy echocardiographic findings of the aortic root 3.6 cm in diameter and the aortic valve of normal tricuspid configuration without regurgitation was presented to our clinic at the 26th gestational week with severe chest pain that began 3 hours before admission

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Summary

Introduction

Aortic dissection (AD) is a serious condition with possible lethal outcome (1). Aortic dissection carries a high risk of maternal mortality and, if prepartum, fetal mortality as well (2). Case Report 1 A 30-year-old patient with Marfan’s syndrome showing prepregnancy echocardiographic findings of the aortic root 3.6 cm in diameter and the aortic valve of normal tricuspid configuration without regurgitation was presented to our clinic at the 26th gestational week with severe chest pain that began 3 hours before admission. Case Report 3 A 25-year-old patient with Marfan’s syndrome from a remote rural area was admitted to our clinic for a surgical repair of an aortic aneurysm, diagnosed during her pregnancy, without any echocardiographic findings before pregnancy. Three and a half months earlier, at the 38th week of gestation, the patient had given birth to a healthy male newborn weighing 3200 grams with an Apgar score of 9/10 at 1 and 5 minutes by cesarean delivery under general anesthesia. The patient was extubated after 9 hours and was discharged 8 days after the operation

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