Abstract

Introduction: Acute renal failure (ARF) during pregnancy is rareevent and continues to be common in developing countries. Period: 1998-2005. Setting: Nephro-urology unit atChandka Medical College, Larkana. Study Design: Retrospective study. Patients & Methods: 294 cases of AcuteRenal Failure were treated. Among these cases, 72 (24.5%) were pregnancy related in origin. All of these patients wereknown to be previously healthy. Results: Pregnancy related Acute Renal Failure was associated with, post partumhemorrhage was in 20(27.7%), intra uterine death in 20(27.7%) antipartum hemorrhage was 18(25%), preeclampsiaeclampsia in 8(11.11%) and septic abortion and puerperal sepsis in6(8.3%). Among these patients 65(90.3%) requireddialysis therapy because of moderate to severe azotemia. 35(48.61%) patients recovered normal function. 30(46.15%)developed irreversible renal function. Conclusion: Early reorganization of this disorder, improvement of health infrastructure, antenatal health care and intensive supportive therapy, can reduce maternal and fetal mortality and morbidity.

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