Pregnancy Outcomes Following Hysteroscopic Resection of Uterine Septum: Does the Size Matter?

Abstract

Study Objective Septate uterus is a common congenital malformation that is usually linked to obstetrical complications. The aim of our study is to compare pregnancy outcomes after hysteroscopic resection (metroplasty) of minor ( Design A retrospective cohort study. Setting A single tertiary affiliated medical center between January 2010 to March 2019. Patients or Participants All women who underwent hysteroscopic resection of uterine septum between 18-45 years old, followed by a documented pregnancy were included. Interventions Septum size was evaluated during operative hysteroscopy by the surgeon. Two groups were defined based on septum size: 1.minor ( Measurements and Main Results During the study period 57 women met inclusion criteria, of them 20 (35%) had a minor septum and 37 (65%) had a major septum. Baseline parameters including maternal age at metroplasty, Body mass index, parity and previous spontaneous abortions were comparable between the groups. The rate of preterm labor before and following uterine septum resection was comparable between the minor and major septum groups [(5/20 vs. 8/37; p=0.764), (3/20 vs. 11/37; p=0.182) respectively], however; decrease rate were observed in the minor group and increased in the major group. Linear regression analysis didn't find septum size to be associated with gestationl a age at delivery (P=-0.26; P=0.15) Conclusion Pregnancy outcomes following uterine metroplasty were comparable between minor and major septum groups. Further studies need to be done in order to strengthen our finding.