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Abstract
[Figure: see text].
Highlights
In pregnancy in well-resourced settings, limited data suggest that higher blood pressure (BP) visit-to-visit variability may be associated with adverse pregnancy outcomes
Variation in both systolic and diastolic blood pressure measurements between prenatal visits is associated with a progression to high blood pressure
Changes occurring in blood pressure levels during pregnancy are associated with adverse outcomes for both mothers and babies and may be useful as an indicator to provide preventative care to women in need
Summary
In pregnancy in well-resourced settings, limited data suggest that higher blood pressure (BP) visit-to-visit variability may be associated with adverse pregnancy outcomes. Higher BP visit-to-visit variability was associated with increased odds, per a SD increase in BP variability measure, of (1) hypertension (systolic: OR, 2.09 [1.98–2.21] for SD and 1.52 [1.45–1.60] for ARV; diastolic: OR, 2.70 [2.54–2.87] for SD and 1.86 [1.76–1.96] for ARV); and (2) the composite outcome (systolic: OR, 1.10 [1.06–1.14] for SD and 1.06 [1.02–1.10] for ARV; diastolic: OR, 1.07 [1.03–1.11] for SD and 1.06 [1.02–1.09] for ARV). In a large study of pregnant women that took place across three countries, both higher blood pressure levels and greater variation in prenatal visit blood pressure measurements were associated with higher rates of adverse maternal and perinatal outcomes. This was the case for both women with normal and high blood pressure levels
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