Abstract
Immunoconflict pregnancy and hemolytic disease of the fetus and newborn remain, despite more than half a century of history, urgent problems in the field of obstetrics and neonatology and continue to be one of the causes of perinatal morbidity. The discovery by Landsteiner and Wiener in 1940 of a causal relationship between Rh isosensitization and hemolytic disease of the newborn (HDN) formed the basis of new branches in immunohematology and perinatology.
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