Abstract

The daily transplantation of the mammalian anterior pituitary into the adult albino mouse or rat results in the development of a greatly increased number of ovarian follicles,1 and is followed by super-ovulation. The number of ova liberated by one ovary varies from 20 to 48, as determined by a study of serial sections of the uterine tubes.2Daily intramuscular transplantations of 2 mouse pituitaries into adult female mice, beginning the first day of the dioestrum, resulted in mating within 12 hours after the second treatment. The animals were killed on the ninth or tenth day of pregnancy. The number of uterine implantations found on the ninth or tenth day was between 19 and 29. Recovery of normal fetuses at this time has not been constant, because of failure of fertilization or implantation in some cases. Another group of similarly treated animals will be permitted to go to term.

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