Abstract

Given the possible medical complications, risks, and the need for informed decision making, pregnancy after kidney transplantation is a serious and difficult issue. In this article, we summarize aspects related to pregnancy counselling for kidney transplant recipients based on past research. Kidney transplant recipients tend to have overall higher rates of preterm deliveries, low-birthweight babies, and caesarean section than the general population. There have been instances of maternal complications such as preeclampsia, allograft loss, and urinary tract infections during pregnancy; in particular, hypertension is a common problem among kidney transplant recipients. Pregnancy counselling should start when a recipient chooses renal replacement therapy, and the counselling program should be tailored to the recipient's life cycle and treatment period. It is necessary to explain the essential conditions for pregnancy, such as the need to change to a safe drug, ensure stable kidney function, and wait one to two years after transplantation before conception. Medical staff should be informed about menstrual recovery after transplantation, contraception, and unexpected pregnancy. When a recipient becomes pregnant, it is necessary to convey information about the mode of delivery and breastfeeding. The contents of pregnancy counselling must be modified according to recipient needs, and detailed discussions are needed between medical staff and transplant recipients. Medical staff should support recipients and their family during the decision-making process before conception. It is essential for kidney transplant recipients to discuss the topic of pregnancy with transplantation physicians, so as to give birth safely and maintain their health with a donated kidney.

Highlights

  • Women with end stage renal disease often have difficulty conceiving through spontaneous pregnancy, and many suffer from infertility [1]

  • We summarize aspects related to pregnancy counseling for kidney transplant recipients based on past research

  • Kidney transplant recipients have to avoid the use of mycophenolic acid or mTOR inhibitors during pregnancy [9]. It is of importance for kidney transplant recipients to discuss the prospect of pregnancy with transplantation physicians, so as to give birth safely and maintain their health with a donated kidney

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Summary

Introduction

Women with end stage renal disease often have difficulty conceiving through spontaneous pregnancy, and many suffer from infertility [1]. Kidney transplantation has been shown to improve fertility and increase the possibility of pregnancy [1,2]. Given the possible medical complications, risks, and the need for informed decision making, pregnancy after kidney transplantation is a serious and difficult issue.

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