Abstract
Pregnancy complicating malignancy occurs 1 in 1000 deliveries. Lymphoma associated pregnancy has become increasing during the past few years and is the fourth most commonly occurred malignancy in pregnancy. Most of the cases reported are Hodgkin's lymphoma. Primary mediastinal large B-cell lymphoma is a rare disease of the subtype of non-Hodgkin's lymphoma. The optimal treatment remains non prospective and mainly dependent upon a personal experience due to its rarity. The issue becomes more complicated as its management involved an ethical issue with the characteristics of the non-Hodgkin's lymphoma being more advanced and wide spread as its counterpart during pregnancy. We report a case of primary mediastinal large B-cell lymphoma associated with pregnancy that result in fetal demise at 29 gestational ages. Severe congested heart failure imposed by the chemotherapy was noted during the treatment period.
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