Pregnancy-associated erythema annulare centrifugum

Abstract

Erythema annulare centrifugum (EAC) is the most common form of gyrate erythemas, which is sometimes linked to underlying diseases and conditions such as immunological disorders, infections, malignancy, foods, drugs, stress, or even pregnancy. Pregnancy-associated EAC is rare and only a few cases have been reported. We herein report the case of a Taiwanese woman who presented with typical EAC lesions during pregnancy, which spontaneously resolved after delivery. This is the first time such a case has been reported in Taiwan. A 34-year-old healthy woman presented to the Department of Dermatology with a 2-week history of asymptomatic skin eruptions that appeared in the 32nd week of her first pregnancy. Clinical examination showed one annular erythematous plaque with trailing scales on her left lower leg (Fig. 1A), which progressed to polycyclic scaly erythema with central clearing on bilateral sides (Fig. 1B) within 1 month. The EAC was diagnosed clinically. All laboratory test results were within normal limits. A body lotion was suggested because the patient was concerned about the possible risk of systemic or topical medication to fetus. At her 38th week, the woman gave birth to a healthy baby, weighing 2550 g. All skin lesions gradually disappeared