Pregnancy and postpartum period in women with Charcot Marie Tooth: review

Abstract

Background: Charcot-Marie-Tooth (CMT) is a hereditary motor and sensory neuropathy that affects the individual in a distal, symmetrical and progressive. Pregnant women with CMT may present greater risks and complications, and the pregnancypuerperal cycle can also impact the clinical condition. Aims: Describe the puerperal pregnancy cycle with CMT, highlighting the main complications Methods: Electronic research by descriptors: Charcot Marie Tooth and Complications in Pregnancy. Portuguese, English, Spanish and Italian were included; no time restriction. Results: The rates of complications during pregnancy and delivery were mostly similar to the reference population, except for the rate of placenta previa, use of forceps and postpartum bleeding. Normal delivery was the route with the highest rates, but there is a change in the obstetric scenario. There were exacerbation of symptoms during pregnancy or postpartum, with some cases of recovery. Conclusion: CMT does not promote an increase in serious complications for the pregnant woman or for the offspring from pregnancy to postpartum, and pregnancy can negatively influence the progression of the disease.