Pregnancy and live birth rate after fresh embryo transfer versus freeze-all strategy: A prospective observational study

Abstract

Objectives. To evaluate which type of embryo transfer (ET) has a superior pregnancy rate. Material and method. Prospective observational non-randomized study including 79 women that underwent 145 ET. Outcomes. The results show that the highest biochemical pregnancy rate (BPR) was in the fresh day 3 ET group (47.62%), but in this group there were also the highest abortion rate (80%) and the highest premature birth rate (100%), giving that, after 21 fresh day 3 ET did not result any term live birth. The frozen day 3 embryo has the lowest BPR (30%), but also the lowest abortion rate (33.33%) and the lowest premature birth rate (0%), in the present study after 13 frozen day 3 ET resulting 2 full-term births (15.38%). The results for the fresh day 5 blastocyst show a good BPR (43.48%), a low abortion rate (33.33%) and the lowest premature birth rate (0%), giving that in the study performed after 23 day 5 ET resulted 4 newborns at term (15.38%). The frozen day 5 blastocyst has a very good BPR (46.07%), the highest birth rate (21.62%), a high abortion rate (37.14%) and a low premature birth rate (7.41%), taking into account that in the present study after 89 day 5 frozen ET resulted 24 newborns, of which 22 full-term births (24.71%). Conclusions. The use of frozen day 5 blastocysts had the best results in terms of the ultimate goal - the birth of a live fetus at term.