Pregnancies in women with uterine malformation, treated obstruction of hemivagina and ipsilateral renal agenesis

Abstract

The aim of this study was to evaluate the outcome of pregnancies in women who had uterine malformation and surgically treated obstructed hemivagina with ipsilateral renal agenesis. The study group comprised 21 women with malformed uterus (12 didelphic, 6 septate and 3 bicornuate uterus). All of them had a history of surgical excision of the longitudinal vaginal septum caused obstructed hemivagina and ipsilateral renal agenesis. All pregnancies and possible surgical interventions were evaluated during the follow-up period (median 13.2years). Thirteen out of 21 women attempting pregnancy conceived. They produced 22 pregnancies, 17 (77%) were contralateral to the treated obstructed hemivagina and unilateral renal agenesis. The median interval between surgical treatment of obstructed hemivagina and the first pregnancy was 10.5years. Twenty (91%) pregnancies ended in delivery of a living infant. Preeclampsia (14%), preterm delivery (36%), high frequency (38%) of fetal breech presentation and the cesarean section rate (67%) were found. Accurate diagnosis and appropriate surgery to open an obstructed hemivagina in adolescence assure fertility. Preterm birth is associated with malformed uterus and unilateral renal agenesis may predispose to preeclampsia.