Abstract

Vaginal pH modulator (VPM; Phexxi®) is a non-hormonal, woman-controlled gel for prevention of pregnancy. In the phase 3 AMPOWER trial (NCT03243305), the seven-cycle cumulative pregnancy percentage was 13.7% with typical-use and 9.99% with perfect-use as determined by the Kaplan-Meier method. The objective of this post hoc analysis was to determine the chance of becoming pregnant by act of intercourse.

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