Abstract
Pregabalin was firstly used as an anti-epileptic drug, but later it there was found a new indication, especially generalized anxiety and neuropathic pain. Duloxetine was firstly used in the treatment of diabetic neuropathy, but in later years it was registered in the treatment of major depressive episodes and generalized anxiety. Both are very effective, but their use is limited by reimbursement recommendations. The paper presents situations in which the use of these drugs can give significant benefits.
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