Abstract

Background: Biopsy is a surgical procedure to obtain tissue of living organism for its histopathological examination, usually to have a diagnosis of early disease progression. Broadly Biopsy can be classified as incisional or excisional biopsy. Depending on the topography involved, the biopsy can be obtained from the oral mucosa in its different locations, the salivary glands, bone, lymph nodes, and other head and neck tissues. Major cause for a biopsy is histopathological confirmation of suspected benign or malignant lesions, non-healing ulcers and major bony lesions after radiographical and clinical investigations. In South Asia biopsy is still gold standard for suspected lesions especially cancers. Objective: Our study’s objective was to evaluate the most frequent oral biopsy technique employed at the dental section, of Dow University of Health Sciences Karachi. Methodology: A cross sectional study was conducted using previously recorded data about biopsy technique employed in dental section, having sample size of 644.Using SPSS ver 21.0, Chi-square goodness of fit test was apply to determine proportion difference among different biopsy techniques and chi-square test of association was applied to see proportion differences among male and female. P-value of less than 0.05 was considered as significant. Results: Incisional biopsy at 55% was the frequent technique employed, with male predominant than excision and punch biopsy techniques. Conclusion: This was a preliminary data on oral biopsy techniques, further related research on a larger population size or multicenter study data would enhance most viable technique employed for oral biopsies in local population

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