Abstract
Introduction: There are no studies on the use of dexketoprofen for postoperative pain control in patients undergoing laparoscopic cholecystectomy. Purpose: To assess if the timing of dexketoprofen administration influences the intensity of postoperative pain in patients undergoing laparoscopic cholecystectomy. Materials and methods used: Experimental, longitudinal, double-blind, randomized study. 50 mg of dexketoprofen diluted in 50 ml of 0.9% saline was administered to 50 patients divided into two groups: Pre-operative group: the substance was administered one hour before the beginning of surgery. Trans-operative group: the substance was administered at the moment when the gallbladder was separated from the liver base. The Numerical Pain Scale was evaluated and the number of doses and the total dose of tramadol that the patients received as analgesic rescue was quantified. Results: Administration of dexketoprofen before starting laparoscopic cholecystectomy tends to reduce the intensity of postoperative pain without being statistically significant. Conclusion: The timing of dexketoprofen administration has no impact on postoperative pain in patients operated for laparoscopic cholecystectomy.
Highlights
There are no studies on the use of dexketoprofen for postoperative pain control in patients undergoing laparoscopic cholecystectomy
Prophylactic vs. postoperative analgesia, both with ketorolac, have been compared and it has been found that the average postoperative ANE was lower for the prophylactic analgesia group; the rescue dose was necessary in 7% of the patients in the preventive analgesia group and 53% in the postoperative analgesia group [13]
The results show that the addition of dexketoprofen trometamol in the analgesia lowers VAS scores, increases patient satisfaction, and decreases opioid consumption [9]
Summary
There are no studies on the use of dexketoprofen for postoperative pain control in patients undergoing laparoscopic cholecystectomy. Purpose: To assess if the timing of dexketoprofen administration influences the intensity of postoperative pain in patients undergoing laparoscopic cholecystectomy. Analgesic interventions occur before the surgical incision, to prevent central and peripheral sensitization, as well as the possible evolution to chronic pain. There is another concept called Pre-emptive analgesia; this is applied after the tissue damage, that is, after the beginning of the surgery, when it is very probable that the sensitization mechanisms have already been established [3, 4].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
