Abstract
(N Engl J Med. 2022;386:1817–1832. doi: 10.1056/NEJMra2109523) Preeclampsia affects 2% to 4% of global pregnancies, targeting low- and middle-income countries specifically, and it results in serious complications for 5% to 20% of women. Preeclampsia often causes or contributes to endothelial damage, increased peripheral vascular resistance, hypertension, pulmonary edema, hemorrhagic stroke, ischemic encephalopathy, kidney, liver, hematologic, and perinatal injury. Demographic characteristics, medical history, current pregnancy characteristics, physiological abnormalities, abnormal laboratory test results, and ultrasonography abnormalities are risk factors for preeclampsia. These risk factors play a critical role in early identification and treatment during pregnancy.
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