Abstract
Introduction: Stroke is one of the important causes of death and disability in Iran. This study aimed to examine the factors influencing the short-term mortality of stroke in Northwest of Iran. Methods: Study population were all patients with confirming the diagnosis of the first-ever stroke who were hospitalized in two referral teaching hospitals from October 2013 to March 2015. They were followed up to 30 days after onset of stroke. A neurology year three resident was responsible for extracting the clinical data and assessment of stroke severity on admission using National Institute of Health Stroke Scale (NIHSS), and information about risk factors and socio-demographic factors were collected using face to face interview. Data were analysed using Cox proportional regression by STATA software version 14. Results: A total of 1036 consecutive patients with first-ever stroke were included in this study. Of them, 228 patients (22%) died within 30 days after stroke accordance. Advanced age was significantly associated with a hazard for early mortality (HR=1.05 95% CI 1.09–1.04), the inverse was true for education level; mortality decreased as the education level increased; it was 25.7 percent among illiterate and 14.3 among patients with higher education. The NIHSS score on admission for 30-days mortality and hemorrhagic stroke were associated with HR=1.11 (95% CI 1.09–1.13) and HR= 1.65 (95% CI 1.15–2.36) respectively. Conclusion: Advanced age, stroke subtype and high NIHSS score are the independent predictors of early mortality in this study. This provides important implications for the clinicians to target the high-risk patients for the specific therapies and management strategies.
Highlights
Stroke is one of the important causes of death and disability in Iran
Materials and Methods This study was conducted in Tabriz, Northwest of Iran and consecutive patients who were admitted to two University referral hospitals; Razi and Imam Reza with a first-ever acute stroke were prospectively included from October 2013 to March 2015
Data were analysed by STATA software version 14; quantitative data were expressed as a mean value ± standard deviation (SD), and only the National Institute of Health Stroke Scale (NIHSS) score at admission was given as a median value
Summary
Stroke is one of the important causes of death and disability in Iran. This study aimed to examine the factors influencing the short-term mortality of stroke in Northwest of Iran. Conclusion: Advanced age, stroke subtype and high NIHSS score are the independent predictors of early mortality in this study This provides important implications for the clinicians to target the high-risk patients for the specific therapies and management strategies. There is a geographical variation in burden of stroke, and the majority of cases are reported from the middle and low-income countries.[3] In recent years advance progression in management and treatment of acute stroke was achieved It is ranked third leading cause of death in developed countries.[4] The one-month case fatality rate of stroke varies in different countries; an average of 22.9% has been reported from 13 countries from various parts of the world.[5] In Iran stroke is one of the most important causes of death and disability. The conservative treatment approach of stroke has been changed towards to active approach,
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
