Predictors of pulmonary complications after lung cancer

Abstract

Objective To analyze the factors of pulmonary complications after lung cancer. Methods The clinical data of 331 patients who underwent lung resection in the First Hospital of Longyan City, Fujian Medical University from January 2017 to December 2018 were analyzed retrospectively. Single factor and multi-factors analyses were performed on the clinical factors that may be associated with pulmonary complications after pulmonary resection to investigate the predictors of pulmonary complications. Results Among the 331 patients in the study, 51 patients developed pulmonary complications and the incidence rate of pulmonary complications was 15.41%. The comparison of the clinical data of patients with and without pulmonary complications were made. Single factor analysis showed that there were statistically significant differences in patients’ gender, preoperative serum albumin level, preoperative c-reactive protein (CRP) level, surgical methods, and whether there was emphysema before surgery (P < 0.05). Multi-factors analysis showed that operation methods(lobectomy , wedge resection) and non-combination of preoperative emphysema were the independent protective factors for postoperative pulmonary complications of lung cancer. Conclusions By evaluating the related factors of pulmonary complications after lung cancer surgery, the pulmonary complications can be reduced, which is beneficial to the management of patients in the perioperative period. Key words: Lung Cancer; Pulmonary Complications; Serum albumin; C-reactive protein; Emphysema