Abstract

The study investigated predictors of poor glycemic control in type 2 diabetes (T2DM). Data on demographics, anthropometric and clinical parameters were collected in a cross-section survey from 140 adults with T2DM, using standard tools/instruments. Glycated hemoglobin (A1C) was assessed as a measure of glycemic control. Majority (83.3%) had poor glycemic control status of which about 95% constitute the elderly. The elderly (OR= 5.90, 95% Cl: 1.66-20.96) were more likely associated with poor glycemic control than the non-elderly (p = 0.006). Adjustment for significant predictor variables: Age, waist-hip ratio (WHR), Fasting plasma glucose (FPG) and Systolic blood pressure (SBP), although attenuated the odds (OR= 5.00, 95% CI: 1.19-20.96) of poor glycemic control, it still remained significantly (p = 0.028) higher in the elderly. Patients outside tight FPG control significantly (p = 0.001) showed poor glycemic cotrol than those within tight FPG (OR= 17.39, 95%Cl: 5.83-51.90), even with attenuated OR (OR= 10.85, 95%Cl: 3.10-37.96) and (OR=12.08, 95%Cl: 3.64-40.09) when non-significant and significant predictor variables were accounted for, respectively. Age, WHR, FPG, and SBP were significantly associated with differences in glycemic control. The elderly and FPG outside tight control showed significantly increased odds of poor glycemic control status.

Highlights

  • The growing incidence of type 2 diabetes mellitus (T2DM) would likely heighten the prevalence of DM globally, with about 11% adults currently suffering with T2DM

  • Adjustment for significant predictor variables: Age, waist-hip ratio (WHR), Fasting plasma glucose (FPG) and Systolic blood pressure (SBP), attenuated the odds (OR= 5.00, 95% confidence intervals (CIs): 1.19-20.96) of poor glycemic control, it still remained significantly (p = 0.028) higher in the elderly

  • Age, WHR, FPG, and SBP were significantly associated with differences in glycemic control

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Summary

Introduction

The growing incidence of type 2 diabetes mellitus (T2DM) would likely heighten the prevalence of DM globally, with about 11% adults (approximately 114 million) currently suffering with T2DM. This is projected to increase to about 150 million by 20401, with 80% of the cases occurring among population in resource-poor settings[2]. Adjustment for significant predictor variables: Age, waist-hip ratio (WHR), Fasting plasma glucose (FPG) and Systolic blood pressure (SBP), attenuated the odds (OR= 5.00, 95% CI: 1.19-20.96) of poor glycemic control, it still remained significantly (p = 0.028) higher in the elderly. Predictors of poor glycemic control in adult with type 2 diabetes in South-Eastern Nigeria.

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