Predictors of paroxysmal atrial fibrillation: Analysis of 24-hour ECG Holter monitoring

Abstract

main predictors of the development of this arrhythmia. Material and methods.A single-center, cross-control study was conducted. Of all 6630 protocols analyzed, according to 24-hour ECG monitoring, AF paroxysm was detected in 97 people as an accidental finding. These patients were included in the main study group. The control group consisted of 99 patients from the same cohort without paroxysmal AF, having the anthropometric and comorbidity parameters similar to the patients of the main group. Results.In the absolute majority (97.9%) of patients in the main group in whom paroxysmal AF was detected, a special variant of extrasystole was revealed – early atrial “P on T” type (versus 4.0% in patients in the control group) [OR 8461.648 (382.1983;187336)]. The number of supraventricular single, paired and group extrasystoles was significantly higher in the main group, but the number of ventricular extrasystoles did not differ significantly. Conclusion.One of the main ECG predictors for the development of paroxysmal AF in asymptomatic patients is the appearance of supraventricular extrasystole of the “P on T” type. In the mechanism of formation of AF paroxysm during supraventricular extrasystole of the “P on T” type, not only electrophysiological mechanisms play a role, but also the heart biomechanics.